Objectives: TASC II recommends bypass for TASC D and low risk TASC C patients, however doesn’t differentiate graft types. We compared percutaneous balloon angioplasty/stenting (PTA/S) and above-knee femoropopliteal bypass (AK-FPB) using PTFE to determine the validity of TASC II in this subgroup.
Methods: Consecutive patients who underwent AK-FPB with PTFE, or PTA/S for TASC-II C (PTA/S-C) or D (PTA/S-D) SFA lesions between 6/2001-4/2007 were identified from our database. Groups were compared for demographics and outcomes (intent-to-treat) using t-test and Kaplan-Meier analysis (SPSS).
Results: 139 limbs (127 patients) were treated (46 AK-FPB, 49 PTA/S-C, 44 PTA/S-D). The mean age was 68.7±10.0, less for AK-FPB than other groups. Renal insufficiency and critical limb ischemia were more common in PTA/S groups, while active smoking and runoff score were significantly higher in AK-FPB. The mean occlusion and stented lengths were 9.9±3.8cm, 24.3±6.6cm in PTA/S-C, and 26.6±5.5cm, 30.0±5.2cm in PTA/S-D. Technical success was 84% in PTA/S-D and 100% in other groups. Mean follow-up was 24.8±18.5 months. Assisted-primary (APP) and secondary (SP) patency of PTA/S-C was significantly better than AK-FPB and PTA/S-D. 24-month PP was better in AK-FPB (73±7%) and PTA/S-C (84±6%) than PTA/S-D (52±8), APP and SP were similar between AK-FPB and PTA/S-D.
Conclusions: PTA/S for TASC C lesions has a superior mid-term patency than AK-FPB. PTA/S-D has similar APP and SP with AK-FPB using PTFE. We suggest TASC-II recommendations be modified to recommend TASC C lesions of SFA, and high-risk patients with TASC D lesions be treated using PTA/S rather than PTFE bypass.
| AK-FPB | PTA/S-C | PTA/S-D | P value | |
| Age | 64.7±8.0 | 71.6±10.4* | 69.4±10.2* | *<0.02 vs AK-POP |
| Renal insufficiency (Cr>1.5mg/dL) | 7% | 31% | 20% | 0.032 |
| Active smoker | 67% | 37% | 39% | 0.002 |
| CLI | 43% | 80% | 73% | 0.001 |
| Runoff score | 2.1±0.7 | 1.7±0.8* | 1.8±0.7** | *0.028, **0.056 vs AK-POP |
| PP (24 mo) | 73±7% | 84±6% | 46±9.6% | <0.001 |
| APP (24 mo) | 78±7% | 98±2% | 62±8% | <0.001 |
| SP (24 mo) | 81±6% | 100% | 66±9% | <0.001 |
| LS (24 mo) | 95±3% | 95±3% | 88±6% | NS |